Epigenetic regulation of Il12 and Il23 gene expression and autoimmune inflammation by the deubiquitinase Trabid
The proinflammatory cytokines interleukin 12 (IL-12) and IL-23 connect innate and adaptive immune responses and are also involved in autoimmune and inflammatory diseases. Here we describe an epigenetic mechanism of Il12 and Il23 gene regulation involving the deubiquitinase Trabid. Deletion of Zranb1...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755875/ |