Comparison of Exome and Genome Sequencing Technologies for the Complete Capture of Protein‐Coding Regions
For next‐generation sequencing technologies, sufficient base‐pair coverage is the foremost requirement for the reliable detection of genomic variants. We investigated whether whole‐genome sequencing (WGS) platforms offer improved coverage of coding regions compared with whole‐exome sequencing (WES)...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
John Wiley and Sons Inc.
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755152/ |