Fluoxetine Protection in Decompression Sickness in Mice is Enhanced by Blocking TREK-1 Potassium Channel with the “spadin” Antidepressant

In mice, disseminated coagulation, inflammation, and ischemia induce neurological damage that can lead to death. These symptoms result from circulating bubbles generated by a pathogenic decompression. Acute fluoxetine treatment or the presence of the TREK-1 potassium channel increases the survival r...

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Bibliographic Details
Main Authors: Vallée, Nicolas, Lambrechts, Kate, De Maistre, Sébastien, Royal, Perrine, Mazella, Jean, Borsotto, Marc, Heurteaux, Catherine, Abraini, Jacques, Risso, Jean-Jacques, Blatteau, Jean-Eric
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755105/