Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress

Silica nanoparticles (SiO2 NPs) cause oxidative stress in respiratory system. Meanwhile, human cells launch adaptive responses to overcome SiO2 NP toxicity. However, besides a few examples, the regulation of SiO2 NP-responsive proteins and their functions in SiO2 NP response remain largely unknown....

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Bibliographic Details
Main Authors: Lin, Chen, Zhao, Xinyuan, Sun, Desen, Zhang, Lingda, Fang, Wenpan, Zhu, Tingjia, Wang, Qiang, Liu, Botao, Wei, Saisai, Chen, Guangdi, Xu, Zhengping, Gao, Xiangwei
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754796/