Loss of UBE3A from TH-expressing neurons suppresses GABA co-release and enhances VTA-NAc optical self-stimulation

Loss of UBE3A from TH-expressing neurons suppresses GABA co-release and enhances VTA-NAc optical self-stimulation

Motivated reward-seeking behaviours are governed by dopaminergic ventral tegmental area projections to the nucleus accumbens. In addition to dopamine, these mesoaccumbal terminals co-release other neurotransmitters including glutamate and GABA, whose roles in regulating motivated behaviours are curr...

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Bibliographic Details
Main Authors: Berrios, Janet, Stamatakis, Alice M., Kantak, Pranish A., McElligott, Zoe A., Judson, Matthew C., Aita, Megumi, Rougie, Marie, Stuber, Garret D., Philpot, Benjamin D.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754338/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754338/

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