Self-Organization of Embryonic Genetic Oscillators into Spatiotemporal Wave Patterns

In vertebrate embryos, somites, the precursor of vertebrae, form from the presomitic mesoderm (PSM), which is composed of cells displaying signaling oscillations. Cellular oscillatory activity leads to periodic wave patterns in the PSM. Here, we address the origin of such complex wave patterns. We e...

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Bibliographic Details
Main Authors: Tsiairis, Charisios D., Aulehla, Alexander
Format: Online
Language:English
Published: Cell Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752819/