Vaccine and Wild-Type Strains of Yellow Fever Virus Engage Distinct Entry Mechanisms and Differentially Stimulate Antiviral Immune Responses

Vaccine and Wild-Type Strains of Yellow Fever Virus Engage Distinct Entry Mechanisms and Differentially Stimulate Antiviral Immune Responses

The live attenuated yellow fever virus (YFV) vaccine 17D stands as a “gold standard” for a successful vaccine. 17D was developed empirically by passaging the wild-type Asibi strain in mouse and chicken embryo tissues. Despite its immense success, the molecular determinants for virulence attenuation...

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Bibliographic Details
Main Authors: Fernandez-Garcia, Maria Dolores, Meertens, Laurent, Chazal, Maxime, Hafirassou, Mohamed Lamine, Dejarnac, Ophélie, Zamborlini, Alessia, Despres, Philippe, Sauvonnet, Nathalie, Arenzana-Seisdedos, Fernando, Jouvenet, Nolwenn, Amara, Ali
Format: Online
Language:English
Published: American Society of Microbiology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752603/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752603/

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