M2 macrophage polarization modulates epithelial-mesenchymal transition in cisplatin-induced tubulointerstitial fibrosis
Cisplatin-induced nephrotoxicity leaded to apoptosis of tubular epithelial cells (ECs) and tubulointerstitial fibrosis through ROS stress and inflammatory cytokines. Tubulointerstitial fibrosis caused by cisplatin might be via activation of resident fibroblasts and epithelial-mesenchymal transition...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
China Medical University
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752551/ |