New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways
Signaling pathways regulated by the receptor CDCP1 play central roles in promoting cancer and in mediating resistance to chemo- and targeted-therapies. In this perspective we briefly summarize these findings as well as data demonstrating poorer outcomes for several malignancies that exhibit elevated...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751911/ |