Peptide mini-scaffold facilitates JNK3 activation in cells

Three-kinase mitogen-activated protein kinase (MAPK) signaling cascades are present in virtually all eukaryotic cells. MAPK cascades are organized by scaffold proteins, which assemble cognate kinases into productive signaling complexes. Arrestin-3 facilitates JNK activation in cells, and a short 25-...

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Bibliographic Details
Main Authors: Zhan, Xuanzhi, Stoy, Henriette, Kaoud, Tamer S., Perry, Nicole A., Chen, Qiuyan, Perez, Alejandro, Els-Heindl, Sylvia, Slagis, Jack V., Iverson, Tina M., Beck-Sickinger, Annette G., Gurevich, Eugenia V., Dalby, Kevin N., Gurevich, Vsevolod V.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751492/