Randomized, Multicenter, Double–Blind Study of the Safety and Efficacy of 1%D-3-Hydroxybutyrate eye drops for Dry Eye Disease

In a previous study, we demonstrated that topical D-beta-hydroxybutyrate ameliorates corneal epithelial erosion and superficial punctate keratopathy in a rat model of dry eye disease. In the current investigation, we performed a prospective, randomized, multicentre, double-blind, placebo-controlled...

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Bibliographic Details
Main Authors: Kawakita, Tetsuya, Uchino, Miki, Fukagawa, Kazumi, Yoshino, Kenichi, Shimazaki, Seika, Toda, Ikuko, Tanaka, Mari, Arai, Hiroyuki, Sakatani, Keiko, Hata, Seiichiro, Okano, Takashi, Tsubota, Kazuo
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749988/