Circulating Carbonic Anhydrase IX and Antiangiogenic Therapy in Breast Cancer

Introduction. Carbonic anhydrase IX (CAIX) is a hypoxia regulated metalloenzyme integral to maintaining cellular pH. Increased CAIX expression is associated with poor prognosis in breast cancer. To explore CAIX as a biomarker for breast cancer therapies, we measured plasma CAIX levels in healthy co...

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Bibliographic Details
Main Authors: Brown-Glaberman, Ursa, Marron, Marilyn, Chalasani, Pavani, Livingston, Robert, Iannone, Maria, Specht, Jennifer, Stopeck, Alison T.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749816/