Hedgehog Signaling Regulates Epithelial-Mesenchymal Transition in Pancreatic Cancer Stem-Like Cells

Hedgehog (Hh) signaling is crucially involved in tumorigenesis. This study aimed to assess the role of Hh signaling in the regulation of epithelial-mesenchymal transition (EMT), stemness properties and chemoresistance of human pancreatic Panc-1 cancer stem cells (CSCs). Panc-1 cells were transfected...

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Bibliographic Details
Main Authors: Wang, Feng, Ma, Ling, Zhang, Zhengkui, Liu, Xiaoran, Gao, Hongqiao, Zhuang, Yan, Yang, Pei, Kornmann, Marko, Tian, Xiaodong, Yang, Yinmo
Format: Online
Language:English
Published: Ivyspring International Publisher 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749361/