Effects of short-term pretreatment with atorvastatin on mobilization of hematopoietic progenitor cells: A double-blind, randomized, controlled trial

Background: Despite recent advances in mobilization techniques, a considerable portion of patients fail to mobilize sufficient number of cells for successful autologous stem cell transplantation. There are several studies available that have demonstrated enhanced mobilization of endothelial progeni...

Full description

Bibliographic Details
Main Authors: Mohammadi, Mehdi, Vaezi, Mohammad, Chahardouli, Bahram, Hadjibabaie, Molouk, Ghavamzadeh, Ardeshir
Format: Online
Language:English
Published: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748693/
id pubmed-4748693
recordtype oai_dc
spelling pubmed-47486932016-02-10 Effects of short-term pretreatment with atorvastatin on mobilization of hematopoietic progenitor cells: A double-blind, randomized, controlled trial Mohammadi, Mehdi Vaezi, Mohammad Chahardouli, Bahram Hadjibabaie, Molouk Ghavamzadeh, Ardeshir Original Article Background: Despite recent advances in mobilization techniques, a considerable portion of patients fail to mobilize sufficient number of cells for successful autologous stem cell transplantation. There are several studies available that have demonstrated enhanced mobilization of endothelial progenitor cells with atorvastatin. Therefore, this prospective trial was conducted to evaluate the mobilizing effect of atorvastatin on hematopoietic progenitor cells. Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2015-10-01 /pmc/articles/PMC4748693/ /pubmed/26865927 Text en Copyright : © International Journal of Hematology-Oncology and Stem Cell Research & Tehran University of Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Mohammadi, Mehdi
Vaezi, Mohammad
Chahardouli, Bahram
Hadjibabaie, Molouk
Ghavamzadeh, Ardeshir
spellingShingle Mohammadi, Mehdi
Vaezi, Mohammad
Chahardouli, Bahram
Hadjibabaie, Molouk
Ghavamzadeh, Ardeshir
Effects of short-term pretreatment with atorvastatin on mobilization of hematopoietic progenitor cells: A double-blind, randomized, controlled trial
author_facet Mohammadi, Mehdi
Vaezi, Mohammad
Chahardouli, Bahram
Hadjibabaie, Molouk
Ghavamzadeh, Ardeshir
author_sort Mohammadi, Mehdi
title Effects of short-term pretreatment with atorvastatin on mobilization of hematopoietic progenitor cells: A double-blind, randomized, controlled trial
title_short Effects of short-term pretreatment with atorvastatin on mobilization of hematopoietic progenitor cells: A double-blind, randomized, controlled trial
title_full Effects of short-term pretreatment with atorvastatin on mobilization of hematopoietic progenitor cells: A double-blind, randomized, controlled trial
title_fullStr Effects of short-term pretreatment with atorvastatin on mobilization of hematopoietic progenitor cells: A double-blind, randomized, controlled trial
title_full_unstemmed Effects of short-term pretreatment with atorvastatin on mobilization of hematopoietic progenitor cells: A double-blind, randomized, controlled trial
title_sort effects of short-term pretreatment with atorvastatin on mobilization of hematopoietic progenitor cells: a double-blind, randomized, controlled trial
description Background: Despite recent advances in mobilization techniques, a considerable portion of patients fail to mobilize sufficient number of cells for successful autologous stem cell transplantation. There are several studies available that have demonstrated enhanced mobilization of endothelial progenitor cells with atorvastatin. Therefore, this prospective trial was conducted to evaluate the mobilizing effect of atorvastatin on hematopoietic progenitor cells.
publisher Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748693/
_version_ 1613536733669883904