First-Line Use of Vemurafenib to Enable Thyroidectomy and Radioactive Iodine Ablation for BRAF-Positive Metastatic Papillary Thyroid Carcinoma: A Case Report

Background. Patients with metastatic or radioactive iodine refractory papillary thyroid carcinoma (PTC) have poor prognosis due to ineffective therapy for this condition beyond surgery and radioactive iodine (RAI or 131I). BRAF mutation occurs in more than 44% of PCT. Tyrosine kinase inhibitors, the...

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Bibliographic Details
Main Authors: Dao, Bao D., Lingvay, Ildiko, Sailors, Joseph, Landay, Michael, Shapiro, Gabriel
Format: Online
Language:English
Published: SAGE Publications 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748501/