TCF7L2 Genotype and α-Cell Function in Humans Without Diabetes
The diabetes-associated allele in TCF7L2 increases the rate of conversion to diabetes; however, the mechanism by which this occurs remains elusive. We hypothesized that the diabetes-associated allele in this locus (rs7903146) impairs insulin secretion and that this defect would be exacerbated by acu...
| Main Authors: | , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
American Diabetes Association
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747457/ |