Prevalence of deleterious ATM germline mutations in gastric cancer patients

Besides CDH1, few hereditary gastric cancer predisposition genes have been previously reported. In this study, we discovered two germline ATM mutations (p.Y1203fs and p.N1223S) in a Chinese family with a history of gastric cancer by screening 83 cancer susceptibility genes. Using a published exome s...

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Bibliographic Details
Main Authors: Huang, Dong-Sheng, Tao, Hou-Quan, He, Xu-Jun, Long, Ming, Yu, Sheng, Xia, Ying-Jie, Wei, Zhang, Xiong, Zikai, Jones, Sian, He, Yiping, Yan, Hai, Wang, Xiaoyue
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747381/