Abnormalities in iNKT cells are associated with impaired ability of monocytes to produce IL‐10 and suppress T‐cell proliferation in sarcoidosis
Sarcoidosis is a multisystem granulomatous disorder characterized by marked T‐cell expansion of T helper 1 (Th1) cells. The cause of T‐cell overactivity is unknown. We hypothesized that interleukin‐10 (IL‐10) production by a yet undefined cell type might be defective, resulting in loss of regulation...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
John Wiley and Sons Inc.
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746743/ |