Targeting the D1-N-methyl-d-aspartate receptor complex reduces l-dopa-induced dyskinesia in 6-hydroxydopamine-lesioned Parkinson’s rats

Targeting the D1-N-methyl-d-aspartate receptor complex reduces l-dopa-induced dyskinesia in 6-hydroxydopamine-lesioned Parkinson’s rats

L-3,4-dihydroxyphenylalanine (l-dopa) remains the most effective therapy for Parkinson’s disease (PD), but its long-term administration is associated with the development of debilitating motor complications known as l-dopa-induced dyskinesia (LID). Enhanced function of dopamine D1 receptor (D1R) and...

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Bibliographic Details
Main Authors: Song, Lu, Zhang, Zhanzhao, Hu, Rongguo, Cheng, Jie, Li, Lin, Fan, Qinyi, Wu, Na, Gan, Jing, Zhou, Mingzhu, Liu, Zhenguo
Format: Online
Language:English
Published: Dove Medical Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745842/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745842/

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