Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans

Despite numerous developed drugs based on glucose metabolism interventions for treatment of age-related diseases such as diabetes neuropathies (DNs), DNs are still increasing in patients with type 1 or type 2 diabetes (T1D, T2D). We aimed to identify novel candidates in adipose tissue (AT) and pancr...

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Main Authors:	Rahimi, Mehran, Vinciguerra, Manlio, Daghighi, Mojtaba, Özcan, Behiye, Akbarkhanzadeh, Vishtaseb, Sheedfar, Fareeba, Amini, Marzyeh, Mazza, Tommaso, Pazienza, Valerio, Motazacker, Mahdi M., Mahmoudi, Morteza, De Rooij, Felix W. M., Sijbrands, Eric, Peppelenbosch, Maikel P., Rezaee, Farhad
Format:	Online
Language:	English
Published:	Impact Journals LLC 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745765/

id	pubmed-4745765
recordtype	oai_dc
spelling	pubmed-47457652016-02-23 Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans Rahimi, Mehran Vinciguerra, Manlio Daghighi, Mojtaba Özcan, Behiye Akbarkhanzadeh, Vishtaseb Sheedfar, Fareeba Amini, Marzyeh Mazza, Tommaso Pazienza, Valerio Motazacker, Mahdi M. Mahmoudi, Morteza De Rooij, Felix W. M. Sijbrands, Eric Peppelenbosch, Maikel P. Rezaee, Farhad Research Paper Despite numerous developed drugs based on glucose metabolism interventions for treatment of age-related diseases such as diabetes neuropathies (DNs), DNs are still increasing in patients with type 1 or type 2 diabetes (T1D, T2D). We aimed to identify novel candidates in adipose tissue (AT) and pancreas with T2D for targeting to develop new drugs for DNs therapy. Impact Journals LLC 2015-08-18 /pmc/articles/PMC4745765/ /pubmed/26337083 Text en Copyright: © 2015 Rahimi et al. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Rahimi, Mehran Vinciguerra, Manlio Daghighi, Mojtaba Özcan, Behiye Akbarkhanzadeh, Vishtaseb Sheedfar, Fareeba Amini, Marzyeh Mazza, Tommaso Pazienza, Valerio Motazacker, Mahdi M. Mahmoudi, Morteza De Rooij, Felix W. M. Sijbrands, Eric Peppelenbosch, Maikel P. Rezaee, Farhad
spellingShingle	Rahimi, Mehran Vinciguerra, Manlio Daghighi, Mojtaba Özcan, Behiye Akbarkhanzadeh, Vishtaseb Sheedfar, Fareeba Amini, Marzyeh Mazza, Tommaso Pazienza, Valerio Motazacker, Mahdi M. Mahmoudi, Morteza De Rooij, Felix W. M. Sijbrands, Eric Peppelenbosch, Maikel P. Rezaee, Farhad Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans
author_facet	Rahimi, Mehran Vinciguerra, Manlio Daghighi, Mojtaba Özcan, Behiye Akbarkhanzadeh, Vishtaseb Sheedfar, Fareeba Amini, Marzyeh Mazza, Tommaso Pazienza, Valerio Motazacker, Mahdi M. Mahmoudi, Morteza De Rooij, Felix W. M. Sijbrands, Eric Peppelenbosch, Maikel P. Rezaee, Farhad
author_sort	Rahimi, Mehran
title	Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans
title_short	Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans
title_full	Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans
title_fullStr	Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans
title_full_unstemmed	Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans
title_sort	age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans
description	Despite numerous developed drugs based on glucose metabolism interventions for treatment of age-related diseases such as diabetes neuropathies (DNs), DNs are still increasing in patients with type 1 or type 2 diabetes (T1D, T2D). We aimed to identify novel candidates in adipose tissue (AT) and pancreas with T2D for targeting to develop new drugs for DNs therapy.
publisher	Impact Journals LLC
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745765/
_version_	1613535557276663808

Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans

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