Methylomics analysis identifies ZNF671 as an epigenetically repressed novel tumor suppressor and a potential non-invasive biomarker for the detection of urothelial carcinoma

The molecular mechanism underlying the lethal phenomenon of urothelial carcinoma (UC) tumor recurrence remains unresolved. Here, by methylation microarray, we identified promoter methylation of the zinc-finger protein gene, ZNF671 in bladder UC tumor tissue samples, a finding that was independently...

Full description

Bibliographic Details
Main Authors: Yeh, Chia-Ming, Chen, Pi-Che, Hsieh, Hsiao-Yen, Jou, Yeong-Chin, Lin, Chang-Te, Tsai, Ming-Hsuan, Huang, Wen-Yu, Wang, Yi-Ting, Lin, Ru-Inn, Chen, Szu-Shan, Tung, Chun-Liang, Wu, Shu-Fen, Chang, De-Ching, Shen, Cheng-Huang, Hsu, Cheng-Da, Chan, Michael W.Y.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745746/