Downregulation of the Yes-Associated Protein Is Associated with Extracellular Matrix Disorders in Ascending Aortic Aneurysms

Previous studies indicate that extracellular matrix (ECM) disorders lead to the apoptosis of Vascular Smooth Muscle Cells (VSMCs), which impairs the aortic wall by reducing the generation of elastic fibers, and ultimately result in ascending aortic aneurysm. The critical role of the Yes-associated p...

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Bibliographic Details
Main Authors: Li, Haiyang, Jiang, Wenjian, Ren, Weihong, Guo, Dong, Guo, Jialong, Wang, Xiaolong, Liu, Yuyong, Lan, Feng, Du, Jie, Zhang, Hongjia
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745276/