Chronic gastroesophageal reflux disease shares genetic background with esophageal adenocarcinoma and Barrett's esophagus
Esophageal adenocarcinoma (EA) is a rapidly fatal cancer with rising incidence in the developed world. Most EAs arise in a metaplastic epithelium, Barrett's esophagus (BE), which is associated with greatly increased risk of EA. One of the key risk factors for both BE and EA is chronic gastroeso...
Main Authors: | Gharahkhani, Puya, Tung, Joyce, Hinds, David, Mishra, Aniket, Vaughan, Thomas L., Whiteman, David C., MacGregor, Stuart |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743691/ |
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