Dendritic and Langerhans cells respond to Aβ peptides differently: implication for AD immunotherapy
Both wild-type and mutated beta-amyloid (Aβ) peptides can elicit an immune response when delivered subcutaneously. However, only mutated forms of Aβ can sensitize dendritic cells when administered intravenously or intraperitoneally. To understand the role of mutation and delivery routes in creating...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742117/ |