Dendritic and Langerhans cells respond to Aβ peptides differently: implication for AD immunotherapy

Both wild-type and mutated beta-amyloid (Aβ) peptides can elicit an immune response when delivered subcutaneously. However, only mutated forms of Aβ can sensitize dendritic cells when administered intravenously or intraperitoneally. To understand the role of mutation and delivery routes in creating...

Full description

Bibliographic Details
Main Authors: Cheng, Jiang, Lin, Xiaoyang, Morgan, David, Gordon, Marcia, Chen, Xi, Wang, Zhen-Hai, Li, Hai-Ning, He, Lan-Jie, Zhou, Shu-Feng, Cao, Chuanhai
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742117/