Lapatinib increases motility of triple-negative breast cancer cells by decreasing miRNA-7 and inducing Raf-1/MAPK-dependent interleukin-6

Lapatinib increases motility of triple-negative breast cancer cells by decreasing miRNA-7 and inducing Raf-1/MAPK-dependent interleukin-6

Lapatinib, a dual epidermal growth factor receptor (EGFR) and HER2 tyrosine kinase inhibitor (TKI), has been approved for HER2-positive breast cancer patients. Nevertheless, its inhibitory effect on EGFR did not deliver clinical benefits for triple-negative breast cancer (TNBC) patients even EGFR ov...

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Bibliographic Details
Main Authors: Hsiao, Yu-Chun, Yeh, Ming-Hsin, Chen, Yun-Ju, Liu, Ju-Fang, Tang, Chih-Hsin, Huang, Wei-Chien
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741977/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741977/

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