Targeting stemness is an effective strategy to control EML4-ALK+ non-small cell lung cancer cells
The fusion between anaplastic lymphoma kinase (ALK) and echinoderm microtubule-associated protein-like 4 (EML4) is a causative factor in a unique subset of patients with non-small cell lung carcinoma (NSCLC). Although the inhibitor crizotinib, as it blocks the kinase activity of the resulting EML4-A...
Main Authors: | , , , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741893/ |