CD19+CD24hiCD38hiBregs involved in downregulate helper T cells and upregulate regulatory T cells in gastric cancer

Regulatory B cells (Bregs) play a critical role in inflammation and autoimmune disease. We characterized the role of Bregs in the progression of gastric cancer. We detected an increase in Bregs producing IL-10 both in peripheral blood mononuclear cells (PBMCs) and in gastric tumors. Multicolor flow...

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Bibliographic Details
Main Authors: Wang, Weiwei, Yuan, Xiangliang, Chen, Hui, Xie, Guohua, Ma, Yanhui, Zheng, Yingxia, Zhou, Yunlan, Shen, Lisong
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741780/