CD19+CD24hiCD38hiBregs involved in downregulate helper T cells and upregulate regulatory T cells in gastric cancer
Regulatory B cells (Bregs) play a critical role in inflammation and autoimmune disease. We characterized the role of Bregs in the progression of gastric cancer. We detected an increase in Bregs producing IL-10 both in peripheral blood mononuclear cells (PBMCs) and in gastric tumors. Multicolor flow...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741780/ |