An epigenetic auto-feedback loop regulates TGF-β type II receptor expression and function in NSCLC

An epigenetic auto-feedback loop regulates TGF-β type II receptor expression and function in NSCLC

The downregulation of transforming growth factor-β (TGF-β) type II receptor (TβRII) expression and function plays a pivotal role in the loss of the TGF-β-induced tumor suppressor function that contributes to lung cancer progression. The aberrant expression of miRNAs has been shown to be involved in...

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Bibliographic Details
Main Authors: Yang, Shanzhong, Cho, Yong-Jig, Jin, Lin, Yuan, Guandou, Datta, Arunima, Buckhaults, Phillip, Datta, Pran K.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741762/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741762/

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