Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis

Despite advances in the development of molecularly targeted therapies, metastatic renal cell carcinoma (RCC) is still incurable. Artesunate (ART), a well-known anti-malarial drug with low toxicity, exhibits highly selective anti-tumor actions against various tumors through generation of cytotoxic ca...

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Bibliographic Details
Main Authors: Jeong, Da Eun, Song, Hye Jin, Lim, Sharon, Lee, Se Jeong, Lim, Joung Eun, Nam, Do-Hyun, Joo, Kyeung Min, Jeong, Byong Chang, Jeon, Seong Soo, Choi, Han Yong, Lee, Hye Won
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741748/