Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells

Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells

Metastatic prostate cancer (PCa) is primarily an androgen-dependent disease, which is treated with androgen deprivation therapy (ADT). Tumors usually develop resistance (castration-resistant PCa [CRPC]), but remain androgen receptor (AR) dependent. Numerous mechanisms for AR-dependent resistance hav...

Full description

Bibliographic Details
Main Authors: Shafi, Ayesha A., Putluri, Vasanta, Arnold, James M., Tsouko, Efrosini, Maity, Suman, Roberts, Justin M., Coarfa, Cristian, Frigo, Daniel E., Putluri, Nagireddy, Sreekumar, Arun, Weigel, Nancy L.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741655/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741655/

Similar Items