Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells

Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells

The overexpression of ATP binding cassette (ABC) transporters makes tumor cells simultaneously resistant to several cytotoxic drugs. Impairing the energy metabolism of multidrug resistant (MDR) cells is a promising chemosensitizing strategy, but many metabolic modifiers are too toxic in vivo. We pre...

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Bibliographic Details
Main Authors: Kopecka, Joanna, Porto, Stefania, Lusa, Sara, Gazzano, Elena, Salzano, Giuseppina, Giordano, Antonio, Desiderio, Vincenzo, Ghigo, Dario, Caraglia, Michele, De Rosa, Giuseppe, Riganti, Chiara
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741618/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741618/

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