The generation and analyses of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic

Phenotypic heterogeneity of human carcinoma lesions, including heterogeneity in expression of tumor-associated antigens (TAAs), is a well-established phenomenon. Carcinoembryonic antigen (CEA), MUC1, and brachyury are diverse TAAs, each of which is expressed on a wide range of human tumors. We have...

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Bibliographic Details
Main Authors: Gabitzsch, Elizabeth S., Tsang, Kwong Yok, Palena, Claudia, David, Justin M., Fantini, Massimo, Kwilas, Anna, Rice, Adrian E., Latchman, Yvette, Hodge, James W., Gulley, James L., Madan, Ravi A., Heery, Christopher R., Balint, Joseph P., Jones, Frank R., Schlom, Jeffrey
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741610/