Cell context-dependent dual effects of EFEMP1 stabilizes subpopulation equilibrium in responding to changes of in vivo growth environment

Cell context-dependent dual effects of EFEMP1 stabilizes subpopulation equilibrium in responding to changes of in vivo growth environment

Conflicting functions of EFEMP1 in cancer have been reported. Using two syngeneic glioma cell lines (U251 and U251-NS) carrying two different principal cell subpopulations that express high or low EGFR, and that are able to interconvert via mis-segregation of chromosome 7 (Chr7), we studied EFEMP1&#...

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Bibliographic Details
Main Authors: Hu, Yuanjie, Ke, Chao, Ru, Ning, Chen, Yumay, Yu, Liping, Siegel, Eric R., Linskey, Mark E., Wang, Ping, Zhou, Yi-Hong
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741566/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741566/

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