TTK activates Akt and promotes proliferation and migration of hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is one of the most malignant cancers with poor clinical outcome. The protein kinase human monopolar spindle 1 (hMps1/TTK) gene expression is significantly increased in HCCs. However, its contributions to hepatocarcinogenesis remain unclear. In this study, we found that...

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Bibliographic Details
Main Authors: Liu, Xing, Liao, Weijia, Yuan, Qing, Ou, Ying, Huang, Jian
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741454/