Reproducibility of SNV-calling in multiple sequencing runs from single tumors
We examined 55 technical sequencing replicates of Glioblastoma multiforme (GBM) tumors from The Cancer Genome Atlas (TCGA) to ascertain the degree of repeatability in calling single-nucleotide variants (SNVs). We used the same mutation-calling pipeline on all pairs of samples, and we measured the ex...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
PeerJ Inc.
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741064/ |