Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes

The ratio of monocytes and lymphocytes (ML ratio) in peripheral blood is associated with tuberculosis and malaria disease risk and cancer and cardiovascular disease outcomes. We studied anti-mycobacterial function and the transcriptome of monocytes in relation to the ML ratio.

Bibliographic Details
Main Authors: Naranbhai, Vivek, Fletcher, Helen A., Tanner, Rachel, O'Shea, Matthew K., McShane, Helen, Fairfax, Benjamin P., Knight, Julian C., Hill, Adrian V.S.
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740301/
id pubmed-4740301
recordtype oai_dc
spelling pubmed-47403012016-02-11 Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes Naranbhai, Vivek Fletcher, Helen A. Tanner, Rachel O'Shea, Matthew K. McShane, Helen Fairfax, Benjamin P. Knight, Julian C. Hill, Adrian V.S. Research Article The ratio of monocytes and lymphocytes (ML ratio) in peripheral blood is associated with tuberculosis and malaria disease risk and cancer and cardiovascular disease outcomes. We studied anti-mycobacterial function and the transcriptome of monocytes in relation to the ML ratio. Elsevier 2015-09-24 /pmc/articles/PMC4740301/ /pubmed/26870787 http://dx.doi.org/10.1016/j.ebiom.2015.09.027 Text en © 2015 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Naranbhai, Vivek
Fletcher, Helen A.
Tanner, Rachel
O'Shea, Matthew K.
McShane, Helen
Fairfax, Benjamin P.
Knight, Julian C.
Hill, Adrian V.S.
spellingShingle Naranbhai, Vivek
Fletcher, Helen A.
Tanner, Rachel
O'Shea, Matthew K.
McShane, Helen
Fairfax, Benjamin P.
Knight, Julian C.
Hill, Adrian V.S.
Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes
author_facet Naranbhai, Vivek
Fletcher, Helen A.
Tanner, Rachel
O'Shea, Matthew K.
McShane, Helen
Fairfax, Benjamin P.
Knight, Julian C.
Hill, Adrian V.S.
author_sort Naranbhai, Vivek
title Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes
title_short Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes
title_full Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes
title_fullStr Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes
title_full_unstemmed Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes
title_sort distinct transcriptional and anti-mycobacterial profiles of peripheral blood monocytes dependent on the ratio of monocytes: lymphocytes
description The ratio of monocytes and lymphocytes (ML ratio) in peripheral blood is associated with tuberculosis and malaria disease risk and cancer and cardiovascular disease outcomes. We studied anti-mycobacterial function and the transcriptome of monocytes in relation to the ML ratio.
publisher Elsevier
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740301/
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