Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth

Analysis of mice deficient for myosin IIIa and myosin IIIb shows that class III myosins limit the elongation of stereocilia and of subsequently regressing microvilli, thus contributing to the early hair bundle shaping.

Bibliographic Details
Main Authors: Lelli, Andrea, Michel, Vincent, Boutet de Monvel, Jacques, Cortese, Matteo, Bosch-Grau, Montserrat, Aghaie, Asadollah, Perfettini, Isabelle, Dupont, Typhaine, Avan, Paul, El-Amraoui, Aziz, Petit, Christine
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738386/
Description
Summary:Analysis of mice deficient for myosin IIIa and myosin IIIb shows that class III myosins limit the elongation of stereocilia and of subsequently regressing microvilli, thus contributing to the early hair bundle shaping.