Obesity Reduces Cognitive and Motor Functions across the Lifespan
Due to a sedentary lifestyle, more and more people are becoming obese nowadays. In addition to health-related problems, obesity can also impair cognition and motor performance. Previous results have shown that obesity mainly affects cognition and motor behaviors through altering brain functions and...
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| Format: | Online |
| Language: | English |
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Hindawi Publishing Corporation
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737453/ |
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pubmed-4737453 |
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pubmed-47374532016-02-15 Obesity Reduces Cognitive and Motor Functions across the Lifespan Wang, Chuanming Chan, John S. Y. Ren, Lijie Yan, Jin H. Review Article Due to a sedentary lifestyle, more and more people are becoming obese nowadays. In addition to health-related problems, obesity can also impair cognition and motor performance. Previous results have shown that obesity mainly affects cognition and motor behaviors through altering brain functions and musculoskeletal system, respectively. Many factors, such as insulin/leptin dysregulation and inflammation, mediate the effect of obesity and cognition and motor behaviors. Substantial evidence has suggested exercise to be an effective way to improve obesity and related cognitive and motor dysfunctions. This paper aims to discuss the association of obesity with cognition and motor behaviors and its underlying mechanisms. Following this, mechanisms of exercise to improve obesity-related dysfunctions are described. Finally, implications and future research direction are raised. Hindawi Publishing Corporation 2016 2016-01-12 /pmc/articles/PMC4737453/ /pubmed/26881095 http://dx.doi.org/10.1155/2016/2473081 Text en Copyright © 2016 Chuanming Wang et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Wang, Chuanming Chan, John S. Y. Ren, Lijie Yan, Jin H. |
| spellingShingle |
Wang, Chuanming Chan, John S. Y. Ren, Lijie Yan, Jin H. Obesity Reduces Cognitive and Motor Functions across the Lifespan |
| author_facet |
Wang, Chuanming Chan, John S. Y. Ren, Lijie Yan, Jin H. |
| author_sort |
Wang, Chuanming |
| title |
Obesity Reduces Cognitive and Motor Functions across the Lifespan |
| title_short |
Obesity Reduces Cognitive and Motor Functions across the Lifespan |
| title_full |
Obesity Reduces Cognitive and Motor Functions across the Lifespan |
| title_fullStr |
Obesity Reduces Cognitive and Motor Functions across the Lifespan |
| title_full_unstemmed |
Obesity Reduces Cognitive and Motor Functions across the Lifespan |
| title_sort |
obesity reduces cognitive and motor functions across the lifespan |
| description |
Due to a sedentary lifestyle, more and more people are becoming obese nowadays. In addition to health-related problems, obesity can also impair cognition and motor performance. Previous results have shown that obesity mainly affects cognition and motor behaviors through altering brain functions and musculoskeletal system, respectively. Many factors, such as insulin/leptin dysregulation and inflammation, mediate the effect of obesity and cognition and motor behaviors. Substantial evidence has suggested exercise to be an effective way to improve obesity and related cognitive and motor dysfunctions. This paper aims to discuss the association of obesity with cognition and motor behaviors and its underlying mechanisms. Following this, mechanisms of exercise to improve obesity-related dysfunctions are described. Finally, implications and future research direction are raised. |
| publisher |
Hindawi Publishing Corporation |
| publishDate |
2016 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737453/ |
| _version_ |
1613532425742188544 |