Extrinsic factors can mediate resistance to BRAF inhibition in central nervous system melanoma metastases

Extrinsic factors can mediate resistance to BRAF inhibition in central nervous system melanoma metastases

Here, we retrospectively review imaging of 68 consecutive unselected patients with BRAF V600‐mutant metastatic melanoma for organ‐specific response and progression on vemurafenib. Complete or partial responses were less often seen in the central nervous system (CNS) (36%) and bone (16%) compared to...

Full description

Bibliographic Details
Main Authors: Seifert, Heike, Hirata, Eishu, Gore, Martin, Khabra, Komel, Messiou, Christina, Larkin, James, Sahai, Erik
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737278/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737278/

Similar Items