Probing binding hot spots at protein–RNA recognition sites

We use evolutionary conservation derived from structure alignment of polypeptide sequences along with structural and physicochemical attributes of protein–RNA interfaces to probe the binding hot spots at protein–RNA recognition sites. We find that the degree of conservation varies across the RNA bin...

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Bibliographic Details
Main Authors: Barik, Amita, Nithin, Chandran, Karampudi, Naga Bhushana Rao, Mukherjee, Sunandan, Bahadur, Ranjit Prasad
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737170/