Investigating the function of Fc‐specific binding of IgM to P lasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting

Acquired protection from P lasmodium falciparum malaria takes years to develop, probably reflecting the ability of the parasites to evade immunity. A recent example of this is the binding of the Fc region of IgM to VAR2CSA‐type PfEMP1. This interferes with specific IgG recognition and phagocytosis o...

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Bibliographic Details
Main Authors: Stevenson, Liz, Huda, Pie, Jeppesen, Anine, Laursen, Erik, Rowe, J. Alexandra, Craig, Alister, Streicher, Werner, Barfod, Lea, Hviid, Lars
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737123/