Dr Jekyll and Mr Hyde: a strange case of 5-ethynyl-2′-deoxyuridine and 5-ethynyl-2′-deoxycytidine
5-Ethynyl-2′-deoxyuridine (EdU) and 5-ethynyl-2′-deoxycytidine (EdC) are mainly used as markers of cellular replicational activity. Although EdU is employed as a replicational marker more frequently than EdC, its cytotoxicity is commonly much higher than the toxicity of EdC. To reveal the reason of...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Royal Society
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736823/ |