ADAR1 Suppresses the Activation of Cytosolic RNA-Sensing Signaling Pathways to Protect the Liver from Ischemia/Reperfusion Injury

ADAR1 Suppresses the Activation of Cytosolic RNA-Sensing Signaling Pathways to Protect the Liver from Ischemia/Reperfusion Injury

Excessive inflammation resulting from activation of the innate immune system significantly contributes to ischemia/reperfusion injury (IRI). Inflammatory reactions in both IRI and infections share the same signaling pathways evoked by danger/pathogen associated molecular pattern molecules. The cytos...

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Bibliographic Details
Main Authors: Wang, Hui, Wang, Guoliang, Zhang, Liyong, Zhang, Junbin, Zhang, Jinxiang, Wang, Qingde, Billiar, Timothy R.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735287/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735287/

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