One-step multiplex real-time RT-PCR assay for detecting and genotyping wild-type group A rotavirus strains and vaccine strains (Rotarix® and RotaTeq®) in stool samples
Background. Group A rotavirus (RVA) infection is the major cause of acute gastroenteritis (AGE) in young children worldwide. Introduction of two live-attenuated rotavirus vaccines, RotaTeq® and Rotarix®, has dramatically reduced RVA associated AGE and mortality in developed as well as in many develo...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
PeerJ Inc.
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734446/ |