One-step multiplex real-time RT-PCR assay for detecting and genotyping wild-type group A rotavirus strains and vaccine strains (Rotarix® and RotaTeq®) in stool samples

Background. Group A rotavirus (RVA) infection is the major cause of acute gastroenteritis (AGE) in young children worldwide. Introduction of two live-attenuated rotavirus vaccines, RotaTeq® and Rotarix®, has dramatically reduced RVA associated AGE and mortality in developed as well as in many develo...

Full description

Bibliographic Details
Main Authors: Gautam, Rashi, Mijatovic-Rustempasic, Slavica, Esona, Mathew D., Tam, Ka Ian, Quaye, Osbourne, Bowen, Michael D.
Format: Online
Language:English
Published: PeerJ Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734446/