Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring

Epigenetic inheritance (EI) of metabolic phenotypes via the paternal lineage has been shown in rodent models of diet-induced obesity (DIO). However, the factors involved in soma-to-germline information transfer remain elusive. Here, we address the role of alterations in insulin, leptin, and adiponec...

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Bibliographic Details
Main Authors: Bönisch, Clemens, Irmler, Martin, Brachthäuser, Laura, Neff, Frauke, Bamberger, Mareike T., Marschall, Susan, Hrabě de Angelis, Martin, Beckers, Johannes
Format: Online
Language:English
Published: Springer US 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731435/