Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures

Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures

Bone mineral density (BMD) is a measure of osteoporosis and is useful in evaluating the risk of fracture. In a genome-wide association study of BMD among 20,100 Icelanders, with follow-up in 10,091 subjects of European and East-Asian descent, we found a new BMD locus that harbours the PTCH1 gene, re...

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Bibliographic Details
Main Authors: Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Gudjonsson, Sigurjon A., Sigurdsson, Asgeir, Center, Jacqueline R., Lee, Seung Hun, Nguyen, Tuan V., Kwok, Timothy C.Y., Lee, Jenny S.W., Ho, Suzanne C., Woo, Jean, Leung, Ping-C., Kim, Beom-Jun, Rafnar, Thorunn, Kiemeney, Lambertus A., Ingvarsson, Thorvaldur, Koh, Jung-Min, Tang, Nelson L.S., Eisman, John A., Christiansen, Claus, Sigurdsson, Gunnar, Thorsteinsdottir, Unnur, Stefansson, Kari
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729819/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729819/

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