Analgesic exposure in pregnant rats affects fetal germ cell development with inter-generational reproductive consequences

Analgesic exposure in pregnant rats affects fetal germ cell development with inter-generational reproductive consequences

Analgesics which affect prostaglandin (PG) pathways are used by most pregnant women. As germ cells (GC) undergo developmental and epigenetic changes in fetal life and are PG targets, we investigated if exposure of pregnant rats to analgesics (indomethacin or acetaminophen) affected GC development an...

Full description

Bibliographic Details
Main Authors: Dean, Afshan, van den Driesche, Sander, Wang, Yili, McKinnell, Chris, Macpherson, Sheila, Eddie, Sharon L., Kinnell, Hazel, Hurtado-Gonzalez, Pablo, Chambers, Tom J., Stevenson, Kerrie, Wolfinger, Elke, Hrabalkova, Lenka, Calarrao, Ana, Bayne, Rosey AL, Hagen, Casper P., Mitchell, Rod T., Anderson, Richard A., Sharpe, Richard M.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728385/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728385/

Similar Items