Route of delivery influences biodistribution of human bone marrow-derived mesenchymal stromal cells following experimental bone marrow transplantation

Mesenchymal stromal cells (MSCs) have shown promise as treatment for graft-versus-host disease (GvHD) following allogeneic bone marrow transplantation (alloBMT). Mechanisms mediating in vivo effects of MSCs remain largely unknown, including their biodistribution following infusion. To this end, huma...

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Bibliographic Details
Main Authors: Wang, Fangjing, Eid, Saada, Dennis, James E, Cooke, Kenneth R, Auletta, Jeffery J, Lee, Zhenghong
Format: Online
Language:English
Published: Journal of Stem Cells and Regenerative Medicine 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728214/