Primary Intracranial Leptomeningeal Melanomatosis
Primary intracranial malignant melanoma is a very rare and highly aggressive tumor with poor prognosis. A 66-year-old female patient presented a headache that had been slowly progressing for several months. A large benign pigmented skin lesion was found on her back. A brain MRI showed multiple linea...
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| Format: | Online |
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The Korean Neurosurgical Society
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728095/ |
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pubmed-47280952016-01-27 Primary Intracranial Leptomeningeal Melanomatosis Kim, Do-Hyoung Choi, Chan-Young Lee, Chae-Heuck Joo, Mee Case Report Primary intracranial malignant melanoma is a very rare and highly aggressive tumor with poor prognosis. A 66-year-old female patient presented a headache that had been slowly progressing for several months. A large benign pigmented skin lesion was found on her back. A brain MRI showed multiple linear signal changes with branching pattern and strong enhancement in the temporal lobe. The cytological and immunohiostochemical cerebrospinal fluid examination confirmed malignant melanoma. A biopsy confirmed that the pigmented skin lesion on the back and the conjunctiva were benign nevi. We report a case of primary intracranial malignant melanoma and review relevant literatures. The Korean Neurosurgical Society 2015-12 2015-12-31 /pmc/articles/PMC4728095/ /pubmed/26819692 http://dx.doi.org/10.3340/jkns.2015.58.6.554 Text en Copyright © 2015 The Korean Neurosurgical Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Kim, Do-Hyoung Choi, Chan-Young Lee, Chae-Heuck Joo, Mee |
| spellingShingle |
Kim, Do-Hyoung Choi, Chan-Young Lee, Chae-Heuck Joo, Mee Primary Intracranial Leptomeningeal Melanomatosis |
| author_facet |
Kim, Do-Hyoung Choi, Chan-Young Lee, Chae-Heuck Joo, Mee |
| author_sort |
Kim, Do-Hyoung |
| title |
Primary Intracranial Leptomeningeal Melanomatosis |
| title_short |
Primary Intracranial Leptomeningeal Melanomatosis |
| title_full |
Primary Intracranial Leptomeningeal Melanomatosis |
| title_fullStr |
Primary Intracranial Leptomeningeal Melanomatosis |
| title_full_unstemmed |
Primary Intracranial Leptomeningeal Melanomatosis |
| title_sort |
primary intracranial leptomeningeal melanomatosis |
| description |
Primary intracranial malignant melanoma is a very rare and highly aggressive tumor with poor prognosis. A 66-year-old female patient presented a headache that had been slowly progressing for several months. A large benign pigmented skin lesion was found on her back. A brain MRI showed multiple linear signal changes with branching pattern and strong enhancement in the temporal lobe. The cytological and immunohiostochemical cerebrospinal fluid examination confirmed malignant melanoma. A biopsy confirmed that the pigmented skin lesion on the back and the conjunctiva were benign nevi. We report a case of primary intracranial malignant melanoma and review relevant literatures. |
| publisher |
The Korean Neurosurgical Society |
| publishDate |
2015 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728095/ |
| _version_ |
1613528866946547712 |