Loss of epidermal growth factor receptor expression in oral squamous cell carcinoma is associated with invasiveness and epithelial-mesenchymal transition

Inhibition of epidermal growth factor receptor (EGFR) signaling has emerged as a novel therapeutic strategy for the treatment of oral squamous cell carcinoma (OSCC). The EGFR-directed inhibitor cetuximab is currently the only approved targeted therapy for the treatment of OSCC. EGFR status may affec...

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Bibliographic Details
Main Authors: KIMURA, IYO, KITAHARA, HIROKO, OOI, KAZUHIRO, KATO, KOROKU, NOGUCHI, NATUYO, YOSHIZAWA, KUNIO, NAKAMURA, HIROYUKI, KAWASHIRI, SHUICHI
Format: Online
Language:English
Published: D.A. Spandidos 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727181/